Acomplia

Rimonabant, Zimulti

Acomplia Review

Acomplia (Rimonabant, Zimulti) is an appetite suppressant diet pill and smoking cessation drug.

Acomplia represents one of the latest and indeed a most novel method for controlling body weight.

Acomplia acts by obstructing the receptors, which control the food intake and energy expenditure. These receptors exist on cells in the body, including those related to weight gain. Thus resulting in reduced appetite.

Along with effective weight loss, Acomplia discourages bad habits like smoking. It is also an anti-smoking pill and improves HDL(good cholesterol) and triglyceride levels. This benefits diabetes and heart conditions. Usual dosage recommended is 20mg per day based on the advise of your doctor depending on your health.

Acomplia and Zimulti are brand names for Rimonabant. Acomplia is a brand drug manufactured and marketed by the French pharmaceutical company Sanofi-Aventis. Zimulti is a contemplated brand name for Rimonabant, intended for its launch in the US. It has not yet been made saleable in the US market. Acomplia is a brand name for Rimonabant in the UK and rest of Europe, which was launched in June 2006.

Acomplia - How it work

Acomplia is a selective CB1 endocannabinoid receptor antagonist. It works by blocking endogenous cannabinoid binding to neuronal CB1 receptors. Activation of these receptors by endoegenous cannabinoids, such as anadamide, increases appetite. It is the most advanced endocannabinoid receptor antagonist in clinical development and offers a novel therapeutic approach to appetite control and weight reduction.

Acomplia also has potential as a treatment for smoking cessation because the endocannabinoid system is involved in the body's response to tobacco dependence.

Acomplia Clinical Tests

A third of the patients given 20 mg of Acomplia lost more than 10 percent of their initial body weight over a period of two years. Around 62 percent of patients given 20mg Acomplia daily lost at least 5 percent of body weight. Waist circumference at two years was reduced by 3.1 inches (8 cm) in the 20 mg Acomplia group, by 1.9 inches (4.9 cm) in a 5 mg Acomplia group. From the tests, Acomplia at 20 mg was more effective than the lower dose.

Acomplia ingredients

The active ingredient of Acomplia is rimonabant. Each film-coated tablet of Acomplia contains 20mg of rimonabant. It works by blocking specific receptors in the brain and fat tissues called CB1 receptors. Acomplia is indicated in the treatment of obesity and management of body weight as adjunct to diet and exercise.

The other ingredients are: Tablet Core: maize starch, lactose monohydrate, povidone K30 (E1201), croscarmellose sodium (E468), sodium laurilsulfate (E487), miceocrystalline cellulose (E 460), magnesium stearate.

Tablet coating: lactose monohydrate, hypromellose 15 mPa.s (E 464), titanium dioxide (E171), macrogol 3000.

Tablet polishing: carnauba wax (E 903).

Acomplia - How to Take

The usual dose is one 20mg tablet to be taken once daily in the morning before breakfast. Swallow the tablet whole.

You need to start and continue a reduced calorie diet and a physical activity program to get best results. Your doctor should recommend the type of diet and the level of physical activity required, that suits your specific condition and overall health.

Acomplia Side Effects

No pill is without side-effects. Acomplia has a few minor side effects which are very temporary and transient. These include nausea, dizziness, diarrhea, vomiting, hypoglycaemia, anxiety and mood swings.

Acomplia Notes

Acomplia tablets include lactose. If you are intolerant to some sugars, contact your doctor before taking this medicine.

Tell your doctor before you take this medicine:

• If you have impaired liver
• If you have severely impaired renal function
• If you are currently being treated for epilepsy
• If you are less than 18 years of age. There is no information available on the use of Acomplia in people under 18 years of age.

Acomplia should not be taken during pregnancy. Contact your doctor immediately if you become pregnant, think you might be pregnant or are planning to become pregnant while taking Acomplia.

Do not take Acomplia when breast-feeing. Tell your doctor if you are breast-feeding or if you are planning to breast-feed your baby.

Acomplia Storage

This medicinal product does not require any special storage conditions.

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