Caffeine

Caffeine has long been used for weight loss due to its demonstrable thermogenic effects. A study published this year concluded that high caffeine intake was associated with weight loss through thermogenesis and fat oxidation and with suppressed leptin in women. Another randomized double-blind placebo-controlled clinical trial of a product containing ephedrine and caffeine showed that subjects taking the treatment experienced greater weight loss, without an increase in blood pressure, pulse, or the rate of adverse events, and in the absence of any lifestyle treatment to change dietary or exercise behavior.